中 文 | English
沈力
研究助理
: | +86-15250412231 |
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: | lishen0709@gmail.com |
: | www.leeshen.net |
: | 成都 |

2012 - 2016 | 东华大学,本科 | 生物工程 |
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2022 - 2023 | 香港理工大学,硕士研究生 | 生物医学工程 |
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2014 - 2016 | 苏州大学 | 科研助理(兼职) |
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2015.7 - 2015.9 | University of California - San Diego | iDASH暑期实习生 |
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2016 - 2017 | 苏州大学 | 科研助理 |
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2017 - 2018 | Yale University | Postgraduate Associate |
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2018 - 2019 | Rutgers - New Jersey Medical School | Research Assistant |
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2020 - 2023 | 四川大学华西医院 | 研究助理 |
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2013 | 上海科技馆“志愿⼯作积极分⼦”称号 |
2016 | American Medical Informatics Association 最佳学⽣论⽂奖 - 转化⽣物信息学领域 |
生物学实验 | 分⼦克隆,细胞培养,⼩⿏解剖,CRISPR基因编辑。 |
生物信息学 | Bulk RNA-seq分析(差异表达,SNP分析),Single-cell RNA-seq分析(10x Genomics Cell Ranger, Seurat等),⽹络分析(Cytoscape,WGCNA),数据库搭建(MySQL),⽂献/⽹络信息挖掘(CiteSpace,Scrapy,BeautifulSoup等等),数据可视化(ggplot,pandas等等),⽹络开发(Vue,Django)。 |
计算机语言 | R,Python,HTML,MySQL,Linux Shell,JavaScript。 |
期刊论文 | ||
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N/A | CSSKD: A knowledge base for cytokine storm syndrome (first author) |
In preparation |
2021 | Altered nitric oxide induced by gut microbiota reveals the connection between central precocious puberty and obesity (Co-first author) |
Clinical & Translational Medicine |
2021 | MiR-378a-3p as a biomarker for hepatocellular carcinoma diagnosis and prognosis: computational screening with experimental validation | Clinical & Translational Medicine |
2020 | Data-driven microbiota biomarker discovery for personalized drug therapy of cardiovascular disease (first author) |
Pharmacological Research |
2019 | Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity | Nature Immunology |
2019 | In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens | Nature Methods |
2019 | Computer-aided biomarker discovery for precision medicine: data resources, models and applications | Briefings In Bioinformatics |
2019 | Convergent identification and interrogation of tumor-intrinsic factors that modulate cancer immunity in vivo | Cell Systems |
2018 | Biomarker microRNAs for prostate cancer metastasis: screened with a network vulnerability analysis model | Journal of Translational Medicine |
2018 | MiRNA-BD: an evidence-based bioinformatics model and software tool for microRNA biomarker discovery | RNA Biology |
2018 | NDDVD: an integrated and manually curated Neurodegenerative Diseases Variation Database | Database |
2017 | Identification of biomarker microRNAs for predicting the response of colorectal cancer to neoadjuvant chemoradiotherapy based on microRNA regulatory network | Oncotarget |
2016 | Knowledge-guided bioinformatics model for identifying autism spectrum disorder diagnostic MicroRNA biomarkers (first author) |
Scientific Reports |
2016 | Biomarker MicroRNAs for diagnosis, prognosis and treatment of hepatocellular carcinoma: a functional survey and comparison | Scientific Reports |
书籍章节 | ||
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2017 | Physiological informatics: collection and analyses of data from wearable sensors and smartphone for healthcare | Advances in Experimental Medicine and Biology |
2017 | Systems health: a transition from disease management toward health promotion (first author) |
Advances in Experimental Medicine and Biology |
2015 | Understanding amino acid mutations in hepatitis B virus proteins for rational design of vaccines and drugs (Co-first author) |
Advances in Protein Chemistry and Structural Biology |
会议论文 | ||
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2017 | PALME: PAtients Like My gEnome | AMIA Summits on Translational Science Proceedings 2016 |